Plasma renin concentration and the hypotensive effect of bendrofluazide and of atenolol.

نویسندگان

  • R Fagard
  • A Amery
  • J F Deplaen
  • P Lijnen
  • A Missotten
چکیده

1. The anti-hypertensive effect of atenolol was greater than that of bendrofluazide. 2. The change in systolic blood pressure caused by bendrofluazide showed a significant inverse correlation iwth the plasma renin concentration (r=-0-47; P less than 0-01). 3. The correlation between the change in systolic blood pressure caused by atenolol and the plasma renin concentration was not significant (r =0-28; 0-1 greater than P greater than 0-05). 4. Plasma renin concentration was unaffected by atenolol.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension.

The efficacy of various combinations of atenolol, bendrofluazide, and hydraliazine given twice daily was assessed in a double-blind trial on 39 patients with moderate to severe essential hypertension. Concurrent treatment with all three drugs proved most effective and produced a mean reduction in blood pressure of 43/31 mm Hg. In the dosage used, hydrallazine affected only the diastolic blood p...

متن کامل

Amoxycillin and co - trimoxazole in presumed viral respiratory infections of childhood : placebo - controlled trial

It has been suggested that patients with essential hypertension may fall into three groups8: those with high renin levels, who respond best to beta-blockers; those with low renin levels, who respond best to diuretics; and those with normal renin, who respond equally to beta-blockers or diuretics. We could not identify any such subgroups in these few patients or any biochemical of physical marke...

متن کامل

Atenolol and bendrofluazide in hypertension.

The effect of atenolol, a new beta-1-adrenergic receptor blocking agent, was studied in a double-blind cross-over trial in 24 carefully selected hypertensive outpatients. After a four-week run-in period on matching placebo each patient received atenolol 200 mg/day, atenolol 400 mg/day, a combination of atenolol 200/mg day with bendrofluazide 5 mg/day, and bendrofluazide 5 mg/day alone, accordin...

متن کامل

The Effect of Atenolol on Thyroid Hormons in Subclinical Hyperthyroidism

     This Study was performed to evaluate the effect of atenolol on the serum concentration of TT4 and TT3 in subclinical hyperthyroid patients. Due to the i n s u fficient information about the effect of atenolol on serum level of these hormones, the aim of this research was to shade some light on the subject. Fifteen subclinical hyperthyroid patients entered this study. Each patient received ...

متن کامل

Intracellular sodium and the response to nitrendipine or atenolol in African blacks.

The relationship between the hypotensive effect of nitrendipine (N), 20 mg/day (n = 17), or atenolol (A), 100 mg/day (n = 17), and the erythrocyte sodium [( Na]i) and potassium [( K]i) concentrations was investigated in hypertensive African blacks during a randomized double-blind study. After 6 weeks, both treatments significantly reduced supine and standing blood pressures; however, the magnit...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Clinical science and molecular medicine. Supplement

دوره 3  شماره 

صفحات  -

تاریخ انتشار 1976